Factors induced during stress in the brain and/or skin, such as corticotropin-releasing hormone, neuropeptides, neurotrophins and α-melanocyte-stimulating hormone, can activate mast cells to ...

Sanofi acquires Blueprint Medicines Corporation for $9.1bn, gaining revenue-driving Aykavit and pipeline drug BLU-808 ...

Zhejiang Jingke Pharmaceuticals Co. Ltd. has identified mast/stem cell growth factor receptor kit (KIT; c-Kit; CD117) inhibitors reported to be useful for the treatment of cancer, neurodegeneration, ...

The granted patent, titled "Targeting KIT with Splice Switching Oligonucleotides to Induce Apoptosis of Mast Cells," protects Hoth's novel approach of using splice-switching oligonucleotides (SSOs) to ...

Shares of Jasper Therapeutics rose after the company disclosed what it called positive data from a recent trial of its treatment for chronic mast cell diseases. The stock climbed 13%, to $6.32, in ...

For some, the word "histamine" might evoke thoughts of seasonal allergies: runny noses, scratchy throats and itchy eyes. But the molecule also ...