Aminoglycoside-class antibiotics bind ... the potential utility of smFRET as a tool for dissecting the mechanisms of antibiotic action. Figure 1: Aminoglycoside-induced restructuring of the ...

Aminoglycosides can override the stop signal ... and the study revealed a novel mechanism through which future drugs could potentially override the erroneous stop signal. The next step is to ...

An international team of researchers, including scientists of the University of Groningen, has now demonstrated how the antimalarial drug mefloquine can enhance the effect of aminoglycosides ... the ...

A very thrilling and motivating discovery." More information: Yusupov, Marat et al, Mechanism of read-through enhancement by aminoglycosides and mefloquine, Proceedings of the National Academy of ...