Aminoglycoside antibiotics (AGAs ... along with the most common bacterial resistance mechanisms, are outlined. Finally, the recent development situation and possibility of new AGAs in the ...

Bacterial antibiotic resistance mechanisms include efflux ... of the mRNA–tRNA complex through the ribosome (such as the aminoglycosides hygromycin B, neomycin, pactamycin and spectinomycin ...

Aminoglycosides are bacteriostatic; they slow down the growth and reproduction of bacteria without killing them. These antibiotics inhibit the synthesis of proteins by binding to the 30S bacterial ...

Antibiotic resistance represents one of ... encoding aminoglycoside-modifying enzymes (AMEs)—the most common mechanism of aminoglycoside resistance. They detected AME genes in around a quarter ...

Nucleotidyltransferases exhibit similar enzymatic activity for the modification of aminoglycosides ... molecular mechanisms ...

These experiments indicated that the single aberrant plant protein killed cells by the same mechanism as the complex mixture of aberrant proteins induced by aminoglycoside antibiotics. But the ...

Choosing the appropriate antibiotics to treat bacterial ... Two primary resistance mechanisms—aminoglycoside enzymatic modification and 16S rRNA methylation—were assessed, and the prevalence ...

Although use of aminoglycosides is associated with low incidence of antibiotic resistance ... However, the underlying mechanisms responsible for the hearing loss were not clearly known until ...

Staphylococcus strains resistant to aminoglycosides and β-lactams ... However, the presence of these mechanisms in isolated, pre-antibiotic-era environments raises questions about how resistance ...

The aminoglycoside antibiotics (amikacin, gentamicin and tobramycin) have been the most widely studied in an attempt to optimize therapeutic drug concentrations and minimize toxicity ...