This study identifies 53BP1 as an interaction partner of GMCL1 (a likely CUL3 substrate receptor). The study seeks to link this finding to regulation of the mitotic surveillance pathway and paclitaxel ...

Cells are the smallest units of life. But even within the same tissue or organ, they are not all identical. New variations arise continuously during cell proliferation. While genetic mutations alter ...

Imagine looking at thousands of scattered puzzle pieces and trying to guess what picture they create. Without any reference ...

Cancer cells respond to stress with greater diversity. Drugs that affect DNA replication, or radiation that causes direct DNA damage, lead to increasingly diverse offspring over multiple cell ...

Download the CBSE Class 11 Biology Syllabus 2025-26 PDF for free. Check the updated course structure, topics, and marking ...

Cell division is an essential biological process that removes aged cells and continuously renews tissues. In the human body, billions of cells divide each day: intestinal cells are completely renewed ...

Cells of a multicellular organism are genetically ... arise during development and are subsequently retained through mitosis. Stable alterations of this kind are said to be 'epigenetic', because ...

Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba 278-8510, Japan Faculty of Pharmaceutical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...