Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Multi-laser picodroplets can be used in single cell analysis, sorting and dispensing - discover how in this article.

More than 50% of patients with systemic lupus erythematosus (SLE) develop lupus nephritis (LN) during the disease, which may ...

However, the similarity in morphology and function of cells in BALF, combined with the diversity of sample processing and analysis methods, can lead to confusion in recognizing and distinguishing ...

Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

The liver performs hundreds of vital functions, including converting nutrients from food into energy, filtering toxins from the blood, and producing bile, a key substance in digestion and waste ...

2 The Danish Twin Registry, University of Southern Denmark, Odense, Denmark 7 Institute of Regional Health Services Research, University of Southern Denmark and Odense Patient data Explorative Network ...

Cystic fibrosis (CF) is a multi-organ disease caused by loss-of-function mutations in CFTR (which encodes the CF transmembrane conductance regulator ion channel). Cystic fibrosis related diabetes ...

Ubiquitylation is a reversible post-translational modification involved in a myriad of cellular functions. A superfamily of approximately 100 ubiquitin-specific proteases, called deubiquitylating ...

The aim of this study was to investigate the functions of semaphorin 4D (SEMA4D) in regulation of neutrophil activation, and its involvement in AAV pathogenesis. Methods Serum levels of soluble SEMA4D ...

Immune functions were also impacted, as evidenced by reduced CD68 and MHCII expression, and decreased phagocytosis in dendritic cells. To conclude, our study provides evidence for lipid accumulation ...

Most neurons that carry signals regarding movement and higher-level functions, such as thinking and reading, are myelinated. Neurons that control feelings of pain and temperature are sometimes ...