A targeted drug therapy has shown potential to reverse cellular damage in Parkinson's disease by regenerating critical brain ...

Stanford researchers discovered that dialing down an overactive enzyme, LRRK2, can regrow lost cellular “antennae” in key ...

Inhibiting an overabundant enzyme saved a key component of a brain signaling pathway that is vital for motor control in a ...

Inhibition of LKKR2 may rescue neurons that are dying due to a type of Parkinson’s disease that is caused by a single genetic mutation.

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

More information: Yu Xun et al, GPR45 modulates Gα s at primary cilia of the paraventricular hypothalamus to control food intake, Science (2025). DOI: 10.1126/science.adp3989 ...

Cilia are notoriously difficult to study. In brain cells, a single cilium, only tens of microns long, extends from a cell’s surface into a jumble of other cells. Using traditional microscopy ...

It is known that tar from cigarette smoke painted on the skin of a mouse for a third to a half the lifetime of the animal can induce a skin carcinoma. 9 It seems reasonable to assume that a ...

If your mouse jumps when the charger is plugged into your laptop, check the power supply. This article lists some working fixes that will help you.

Tiny hairs, or cilia, in a mouse embryo gyrate clockwise, setting up a leftward flow in the surrounding fluid. This fluid flow is then picked up by static cilia, called immotile cilia, located to the ...

Primary cilia (PC) are important signaling hubs, and we here explored their role in colonic pathology. In the colon, PC are mostly present on fibroblasts, and exposure of mice to either chemically ...

Jing Hughes, an endocrinologist at Washington University in St. Louis, was working late in the lab recently, imaging cilia in mouse pancreatic beta cells. These cilia, which are tiny hairlike ...