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Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments ...
Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...
The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...
Translational Medicine Research Center, Sirius University of Science and Technology, Sochi, Russia The ability to reprogram mature, differentiated cells into induced pluripotent stem cells (iPSCs) ...
They are called “Natural Killer” (NK) cells for a reason. These cytotoxic lymphocytes, a part of innate immunity, are the body’s cellular “boots on the ground,” capable of swiftly and ...
Step 3: HSC to NK cell differentiation This step involved the seeding of human CD34+ hematopoietic cells in precoated wells. These were then cultured for 21 days in a medium containing factors ...
Induced pluripotent stem cell-derived CAR-NK cell products such as FT596 eliminate the harvesting, initial shipping, and patient-specific manufacturing as it is off-the-shelf and is available ...
World-First Stem Cell Treatment Reverses Diabetes for a Patient in China, Study Suggests Scientists converted the patient’s own cells into blood sugar-regulating cell clusters before injecting ...
Another difference is that "the patient-specific stem cell–derived islets used in this study were produced from induced pluripotent stem cells generated using chemical reprogramming, which is a ...
There’s use for pluripotent stem cells in disease diagnosis and treatment. Ultimately, Jing says, the hope is to both expand the giant panda population and make it healthier.
The second stage involved turning the pluripotent cells into blood stem cells. “We first make thousands of small floating balls of cells, a few hundred cells in each ball, and direct them to ...
One of its drug candidates, for example, enhances NK-cell and T-cell sensitivity to IL-15. Others are taking advantage of known activating and inhibitory receptors to bolster existing NK cells.
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