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Lipid nanoparticles that engineer CAR T cells in vivo could unlock access for millions of autoimmune patients
Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without ...
eLife17h
HIV-specific CD8+ T-cell responses soon after treatment initiation during acute HIV infection are associated with viral reservoir decline
Antiretroviral therapy (ART) initiated in the acute phase of HIV infection (AHI) results in a smaller viral reservoir. However, the impact of early HIV-specific T-cell responses on long-term reservoir ...
Frontiers19d
Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss
NK cell phenotypes were assessed with comprehensive flow cytometry panels. NK cell function was assessed with degranulation assays and intracellular staining of interferon-γ (IFN-γ), perforin and ...
Frontiers20d
Case Report: Epididymal NK/T-cell lymphoma and adrenal diffuse large B-cell lymphoma are misdiagnosed as tuberculosis: two case reports and literature review
Extranodal NK/T-cell lymphoma(ENKTCL) and diffuse large B-cell lymphoma(DLBCL) are specific subtypes of non-Hodgkin lymphoma(NHL), which lack specific features and ...
PNAS25d
Trans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation
Contributed by Thomas A. Waldmann, November 12, 2019 (sent for review July 8, 2019; reviewed by Thomas R. Malek and Kimberly S. Schluns) ...