UC San Diego researchers have identified the molecular and cellular mechanisms that transform healthy stem cells into oral cancer at the earliest stages of the disease ...

Researchers have discovered how healthy stem cells are transformed into cancer stem cells in the early stages of oral cancer.

The cancer takes root in epithelial cells, the top layer of cells lining these ... triggered a cascade of cellular and molecular changes that reprogrammed normal stem cells into cancer cells in a ...

Nearly 60,000 people are diagnosed with oral cancer in the U.S. every year, according to the American Cancer Society, and the rate of new cases continues to rise.

The T3SS that is encoded on Salmonella pathogenicity island (SPI)-1 is responsible for delivering effectors across the plasma membrane and is involved in the invasion of epithelial cells and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cancers display cellular, genetic and ...