Given the temporal correlation between oligodendrocyte development and synapse elimination, the relationship between synapse elimination and brain diseases, and our findings that oligodendrocytes ...

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune disease of the central nervous ...

Astrocyte allocation during brain development is regulated by Tcf4-mediated fate restriction based on their embryonic origin.

Astrocytes in the brain exhibit regional heterogeneity contributing to regional circuits involved in higher-order brain functions, yet the mechanisms controlling their distribution remain unclear.

The contribution of the lateral/caudal ganglionic eminence to the pool of cortical oligodendrocyte precursor cells is minimal.

Study uncovers how environmental chemicals, specifically organophosphate flame retardants and quaternary compounds, negatively affect oligodendrocyte development, implicating them in potential ...

During this healing process, oligodendrocyte precursor cells (OPCs) migrate to the lesion site and differentiate into mature OLs. This study hypothesized that high mobility group box 1 (HMGB1), one of ...

Fractalkine helps to regulate oligodendrocyte development, a study found, and MS work targeting this protein might aid in remyelination.

These data demonstrate that the loss of differentiating oligodendrocyte precursors is not confined to typical time course of development; rather, it continues into adulthood and greatly reduces the ...

There is loss of oligodendrocytes and alteration of oligodendrocyte subtypes in CTE that might provide new targets for prevention and therapies," said corresponding author Ann McKee, MD, chief of ...