Myelodysplastic syndromes (MDS) are a group of disorders that typically arise in adulthood, especially after the age of 70, ...

HSPCs polarize in contact with bone marrow stromal cells constituting their niche. This study analyses the polarity of ...

The team showed that when BCG was administered to mice in their bladders, the bacteria traveled to their bone marrow — and could actually be cultured directly from it. And it is in the bone ...

Here we describe the initial results of allogeneic bone marrow transplantation in three children with osteogenesis imperfecta, a genetic disorder in which osteoblasts produce defective type I ...

These conditions often result from the dysregulation of osteoclasts—specialized cells responsible for breaking down bone tissue. Today, many promising treatments target the receptor activator of ...

This is enough to downregulate the development of mature osteoclasts without affecting unrelated biological processes as a side effect. Bone-destructive diseases such as osteoporosis and chronic ...

Skeletal stem cells (SSCs) have been isolated from various tissues, including periosteum and bone marrow, where they exhibit key functions in bone biology and hematopoiesis, respectively. The role of ...

Def Leppard guitarist Vivian Campbell has returned to the stage eight months after he underwent a bone marrow transplant in his fight against cancer. Campbell, 62, played with the band on May 15 ...

It was just a couple of days later that she was diagnosed with aplastic anemia, and she was going to need an urgent bone marrow transplant,” Leslie said. The disease attacks your bone marrow, so that ...

1 Orthopaedic Department, Affiliated ZhongShan Hospital of Dalian University, Dalian, Liaoning, China 2 Orthopaedic Medical Research Center, Dalian University, Dalian, Liaoning, China Bone defects ...