Learn how antibody to payload design is crucial for advancing ADC technology in oncology and beyond with expert insights.

"Part of the reason why language models can predict ... One of these modules was trained on hypervariable sequences from about 3,000 antibody structures found in the Protein Data Bank (PDB ...

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

they play an important part in the clearance of immune complexes consisting of antigen, antibody, and components of the complement system. Innate responses frequently involve complement ...

One was trained from 3,000 antibody structures on hypervariable ... but not identical and so the challenge you try to address is, which parts of the model should you change? How should you adapt ...

A team of Ohio State researchers engineered a new antibody that could revolutionize influenza prevention through a nasal ...

Current methods of antibody detection, such as conventional serological assays, are limited in terms of the amount of ...

Even with the exact same antibody and payload, if you change the linker, you get a completely different outcome. ADCs’ generic names have two parts—a first name for the antibody and a second ...

An antibody developed by researchers works against ... escape this treatment because SC27 targets and attaches to multiple parts of the virus's spike protein, including sections that are not ...

"We chose this specific antibody because it targets a part of the influenza virus called the stalk region of the hemagglutinin protein, which stays the same across different flu strains.