Peptide nucleic acids targeting noncanonical DNA and RNA As a molecular biologist, I always enjoy reading articles concerning DNA and RNA.

Peptide Nucleic Acid (PNA): Synthetic molecules that mimic natural nucleic acids but feature a peptide-like backbone, which results in enhanced binding affinity and resistance to enzymatic ...

Peptide nucleic acids progress for gene editing and antisense drugs These lab-made molecules can bind to genes more strongly than DNA and RNA do, making them promising drug candidates and genetic ...

Gene-editing technology based on peptide nucleic acids is administered intravenously in a mouse model of ß-thalassemia, achieves cure with few off-target effects.

Peptide nucleic acid, a synthetic hybrid of protein and DNA, could form the basis of a new class of drugs—and of artificial life unlike anything found in nature ...

Scientists have developed a method for self-assembling nanostructures with gamma-modified peptide nucleic acid, a synthetic mimic of DNA. The process has the potential to impact nanomanufacturing as ...

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine ...

Nucleic Acid and Protein Research at Rockefeller University National Historic Chemical Landmark Dedicated October 20, 2000, at Rockefeller University in New York City, New York. John D. Rockefeller, ...

Summary Peptide Nucleic Acid (PNA) is a synthetic polymer similar to DNA or RNA. PNA can be said to have been born in Denmark, where it was originally developed by Peter E. Nielsen (University of ...

A peptide nucleic acid-based gene editing technique is an essential part of the gene editing toolkit in addition to CRISPR-Cas systems.

Cell-penetrating peptides are a class of short peptides with a length of 5~30 amino acids, which can carry peptides, nucleic acids, small molecules of drugs, and virus particles through cell ...