Feigin points out that mutations in a promoter can affect how much protein is generated by the gene its regulates. In this way these mutations are unlike those usually found in KRAS and p53, for ...

DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a ...

A team of researchers unveils a novel, key aspect of enhancer-mediated regulation of gene expression and proposes a mechanism that explains the tight connection between gene enhancers and promoters.

These new promoters work with AAV as well as other viral and non-viral gene-delivery systems. These new promoters will allow us to deliver larger genes or multiple small genes, and the genes can ...

At specific places called promoters, a complex molecular machinery starts transcribing DNA sequences into mRNA. Interestingly, most genes contain multiple possible sites where transcription can start ...

Characterizing gene promoters and promoter–terminator combinations is crucial for maximizing the benefits of bioengineering applications in plants. However, traditional methods of identifying ...

Researchers demonstrate targeted epigenome editing in the promoter region of several genes using sgRNA/dCas9 complexes Download PDF Copy By Vijay Kumar Malesu Reviewed by Benedette Cuffari, M.Sc ...

DNA packaging: VPS72 helps attach specific proteins to DNA, which affects whether certain genes are turned on or off. Suppressing protective genes: VPS72 adds chemical tags to the promoter of gene ...

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