Our results demonstrated that hirudin treatment alleviated renal injury in UUO rats and improved renal tubule dilation ... induced renal fibrosis by inhibiting renal tubular epithelial cells ...

In response to the inflammation, the renal tubule epithelium cells also generate mediators that potentiate the cascade of inflammation [25]. Experimental studies of AKI - ischemia and reperfusion ...

Kidney disease is one of the leading causes of death and suffering in the 21st century. In 2017, the Global Burden of Disease (GBD) Chronic Kidney Disease ...

These results suggest that periodontal disease enhances renal fibrosis and that this process is related to the TGF-β1/Smad/COL-IV signaling pathway. Among the top five dominant bacteria in the kidney ...

The bilateral renal tissues were rinsed with PBS ... Wnt7b began to accumulate in the villi of proximal convoluted tubule epithelial cells (PCTECs) from day 2 and reached its peak on day 8. Similarly, ...

aInflammation and Immune-Mediated Diseases Laboratory of Anhui Province, The Key Laboratory of Anti-inflammatory of Immune Medicines, Ministry of Education, Anhui Institute of Innovative Drugs, School ...