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Highlights of Dr. Palczewski’s research include: the crystallographic determination of the structures of the native and light-activated GPCR, rhodopsin; the discovery and molecular description of ...

When the eyes detect low light for longer than 20 minutes, the body produces the rhodopsin chemical, which triggers our night vision. When the eyes are exposed to bright light, the rhodopsin ...

The first optogenetic "Chimeric Rhodopsin" gene therapy tested in humans. RV-001 starting dose was generally well tolerated in this open-label trial. RV-001 a gene-agnostic approach for RP patients.

In their paper, titled “Discovery of non-retinoid compounds that suppress the pathogenic effects of misfolded rhodopsin in a mouse model of retinitis pigmentosa,” the team concluded ...

Natural night vision (as opposed to artificial night vision created by binoculars) is created not only by the dilation of the pupils but also by a protein called rhodopsin, which can't be made ...

In the treatment method envisioned by Kurihara, a virus incorporating the light-sensitive protein "rhodopsin" is injected into the eye. When a person suffers from retinitis pigmentosa, even if ...

This can happen with all kinds of genetic information and is particularly common with rhodopsin proteins. “In the process of figuring out a way to get rhodopsins into multi-celled yeast,” said ...

A group of researchers discovered that the rhodopsin -- a protein in the eye that detects light -- of whale sharks has changed to efficiently detect blue light, which penetrates deep-sea water easily.

The research revealed that the whale sharks’ rhodopsin can efficiently detect blue light—the most common wavelength of light in the deep-sea—because two amino acid substitutions shifted the ...