A Cessna 414 crashed into the Pacific Ocean off San Diego, killing all six aboard shortly after takeoff. The pilot issued a ...

Center fielder Jackson Merrill and the San Diego Padres didn't waste much time fretting over Monday night's 8-7, 10-inning loss to the Los Angeles Dodgers.

A new study reveals that eating raw freshwater fish could expose you to dangerous parasitic worms that are spreading across ...

The Los Angeles Chargers will be back in San Diego for two training camp practices this summer, the team announced Thursday.

SAN DIEGO (KGTV) — Lions, tigers, bears and... the first-ever YouTube video? Oh my! The San Diego Zoo has earned international acclaim over the years for its diverse array of animals on display ...

Adha celebration in San Diego [This post contains video, click to play] Source: YouTube Reuters ---------------------------- ...

Get San Francisco vs San Diego baseball betting preview, spread and over/under insights for their matchup on June 4.

SAN DIEGO (FOX 5/KUSI ... Starting April 19, parents who are familiar with the catchy children’s song and YouTube video that took the Internet by storm in 2016 will be able to take their ...

Federal and local authorities in San Diego arrested three men in the U.S. illegally – two from Mexico and one from El Salvador – after they allegedly transported nearly 8,000 pounds of ...

Angry crowds clashed with ICE agents after ICE raided a restaurant in San Diego on May 30, as part of an investigation into ...

The "Big Bang" of the video-sharing world. It was the first-ever clip uploaded to YouTube, 20 years ago. That zoo? The one in San Diego's backyard. On April 23, 2005, YouTube founder Jawed Karim ...

At least three people are dead and seven others, including two children, are missing after a "panga"-style fishing vessel washed ashore near San Diego on May 5, authorities said. Crews responded ...