St. John's wort is a very effective inducer of hepatic CYPs, specifically, CYP3A4, CYP2C9, and CYP1A2. Hyperforin has been found to induce CYP3A4 via activation of pregnane X, an orphan nuclear ...

The herb <b>St John's Wort</b> has been used to treat depression in children as young as six. Boys aged six to 16 who used the herb for depression responded to treatment, according to a pilot trial ...

St John's Wort is a herb which has been proven to be useful in the treatment of mild and moderate depression. In fact, studies show that it is as effective as Prozac, only with far fewer side-effects.