Initially, hit molecules were evaluated via qPCR for dose responsiveness and to confirm the desired splicing activity. Once the desired splicing pattern was confirmed, SMN protein levels were assessed ...

Alternative pre-mRNA splicing is a fundamental mechanism of post-transcriptional gene regulation that creates lineage-specific functional diversity in the proteome. Although heart-specific alternative ...

Abstract: A key challenge of image splicing detection is how to localize integral tampered regions without false alarm. Although current forgery detection approaches have achieved promising ...

The fundraiser supports 21 young athletes from Idaho who have been selected as part of Team USA at the World Jump Rope Championships, held from July 27 to Aug. 3 in Kawasaki. The team qualified ...

Post-transcriptional splicing has emerged as a key layer of gene expression regulation but is challenging to differentiate from co-transcriptional splicing. The authors review methodologies to ...

Private credit fund manager Vivriti Asset Management, a subsidiary of mid-market lender Vivriti Capital, has secured an additional $20 million in senior debt commitments from the Development Bank of ...

The Knight Commission will convene Tuesday, May 20, for what may be one of the most consequential conversations in the history of college athletics. With NCAA President Charlie Baker on the agenda ...

100 Best Movies of 1985 (The Goonies), Ranked by Tomatometer Link to 100 Best Movies of 1985 (The Goonies), Ranked by Tomatometer 89 Best Spy Movies (Spy), Ranked by Tomatometer Link to 89 Best ...

Byju Raveendran, founder of the now cash-strapped edtech giant BYJU’S, has defended the company’s high-profile endorsements featuring actor Shah Rukh Khan and football star Lionel Messi ...

EXCLUSIVE: Netflix has acquired Devil’s Rope, an original spec by Melanie Toast, to be produced by Toby Jaffe. Plot details are under wraps, though sources described the project as a female-led ...