The research findings carry profound implications for cancer treatment strategies, indicating that the activation of the cGAS-STING pathway could transform the landscape of immunotherapy.

The researchers also wanted to activate the TRL4 pathway because it boosts the effects of STING activation. They use agonists, which are any chemicals that can trigger a biological response; in ...

Considered to be one of the greatest revolutions in cancer treatment, immunotherapy enhances the immune system's ability to ...

Researchers have developed an innovative nano-immune agonist that significantly improves immunotherapy ... the cGAS-STING signaling pathway, a key player in innate immune activation.

The cGAS-STING pathway facilitates crosstalk between cancer cells and the tumor microenvironment (TME). The activation of cGAS-STING promotes the release and presentation of cancer antigens ...

Meanwhile, drugs targeting TIM-3, LAG3, VISTA and STING also coming through development ... “We have been researching TIGIT as a novel cancer immunotherapy target for almost 10 years and ...