During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and ...

The specification of T-helper-cell subsets is controlled by networks of lineage-specifying transcription factors, which bind to regulatory elements in genes that encode cytokines and other ...

A key element in the profound immunosuppression ... a potential therapy target for metabolic diseases. Pathogenic T helper type 2 cells (pTh2) are involved in allergic asthma and secrete high ...

New research shows how a specially trained population of immune cells keeps the peace by preventing other immune cells from attacking their own. The study provides a better understanding of immune ...