Lyell Immunopharma announced new clinical data Tuesday from a Phase I/II trial of its dual-targeted CD19/CD20 CAR T-cell therapy for relapsed or refractory large B-cell lymphoma. The company ...

Despite advances, the roles of genetics and microenvironment in CLL are not fully understood, and curative treatments may hinge on a dual approach targeting both.

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer ...

Analysis revealed that patients with T-cell exhausted archetype tumors had significantly higher rates of progressive disease ...

Announcing a new article publication for Zoonoses journal. Because varicella zoster virus (VZV) infections are continually ...

Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases ...

The emergence of machine learning and high-content microscopy suggests potential to more comprehensively define CF activation beyond simply staining α-SMA. Here, we coupled Cell Painting 4 with a ...

Patients with fewer prior lines of therapy had improved overall response rate (ORR) with chimeric antigen receptor (CAR) T-cell therapy lisocabtagene maraleucel (liso-cel; Breyanzi) in patients with ...

Using this approach, Neal et al. were able to produce the first open-source genome-wide perturbation atlas of cell morphology in human cells. The atlas contains 3 genome-wide genotype-phenotype maps ...

Cell morphology describes the shape, size, structure and appearance of a cell, including the arrangement of organelles within the cell. The morphology of a cell is a rich source of information about ...

It develops from the abnormal multiplication of T cells, or T-lymphocytes, a type of white blood cell essential for immune system function. The specific treatment course and prognosis for T-cell ...