A model developed by LMU biophysicists demonstrates how biological processes form the convoluted internal architecture of the ...

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer ...

Eureka reported that an engineered TCRm targeting alpha-fetoprotein (AFP)-MHC complex can effectively redirect CAR-T cells against liver cancer cells. In this study, the crystal structure showed ...

CAR-T cells are, in essence, T-lymphocytes equipped with a next-generation membrane receptor: a structure specifically designed to recognize and attack tumor cells with a precision and sensitivity ...

Despite the remarkable efficacy of CAR-T cell therapies to treat certain blood ... The spongelike structure is also sprinkled with antibodies to activate the T cells and the cytokine IL-2 to ...

Anaplastic large cell lymphomas are rare but aggressive T-cell lymphomas ... that regulate gene activity and are considered a target structure for modern cancer therapies.

Peripheral T-cell lymphoma is a rare and aggressive type of cancer that affects mature T cells. Learn more ... research from 2020 mentions that changes in the DNA’s structure causing ...

Immune cells called T cells are central to the body’s defense against cancer and other threats. Immunologists are fond of car analogies. The T cells that protect us from infections and cancer, they ...