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The palatine or faucial tonsils, commonly known as just tonsils, sit in the back of the throat and consist of lymphatic tissue. Along with the pharyngeal, tubal, and lingual tonsils, they defend ...
When we are exposed to a pathogen, the immune system's B cells swarm to our lymph nodes, spleens, and tonsils. There, those cells mutate in germinal centers—microscopic boot camps that rush the ...
This built-in safeguard allows germinal centers to mass-produce successful clones without compromising antibody quality. The findings, published in Nature , solve the paradox of how the immune ...
Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells ...