Viktor Gyokeres leads the line for Arsenal, finally making his Premier League debut despite spending four seasons at Brighton and Hove Albion earlier in his career. He is not the only fresh face in the Gunners' lineup, though, with Martin Zubimendi slotting into a place in midfield. See Arsenal's starters and substitutes below.

All six of Arsenal's English Premier League wins at Old Trafford have come by a 1-0 scoreline, the most away wins any team has over another with all of them coming by the same scoreline

English Premier League heavyweights start anew in 2025-’26, as returning league runner-up Arsenal visits Manchester United in the season opener for both clubs.