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P142 Hypoxic challenge test (hct) for in-flight oxygen assessments can be avoided in patients with lung disease and low resting pao2
Introduction Hypoxic challenge test consisting of breathing 15% FiO2 for 20 min with blood gas measurements is recommended by BTS guidelines for the assessment of the requirement for in-flight oxygen.
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Cough threshold in patients with chronic obstructive pulmonary disease
BACKGROUND Cough is an important symptom of patients with chronic obstructive pulmonary disease (COPD). The cough threshold to citric acid and capsaicin in patients with COPD and in normal volunteers ...
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S3 The uk’s largest severe asthma multidisciplinary team meeting; experience from the first 18 months
Background Severe asthma comprises 5% of all asthma, but over 50% of the asthma healthcare burden. With multi-disciplinary team (MDT) working there is potential to improve patient outcomes and reduce ...
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Pneumococcal pneumonia trends in adults hospitalised with community-acquired pneumonia over 10 years (2013–2023) and the role of serotype 3
Background With higher valency pneumococcal vaccines on the horizon and new adult immunisation strategies under discussion, we aimed to evaluate the contribution of individual pneumococcal serotypes ...
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Alpha-1 antitrypsin deficiency alleles and severe cystic fibrosis lung disease
Dr R Mahadeva, Department of Haematology, University of Cambridge, MRC Centre, Hills Road, Cambridge CB2 2QH, UK. RESULTS Seventy nine patients were identified (seven dead, 72 transplanted). Two ...
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Effect of salmeterol on respiratory muscle activity during exercise in poorly reversible COPD
3 Department of Statistics (Research & Development), King’s College Hospital, London, UK Correspondence to: Dr W D C Man Respiratory Muscle Laboratory, Guy’s, King’s and St Thomas’ School of Medicine, ...
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Interventions to improve symptoms and quality of life of patients with fibrotic interstitial lung disease: a systematic review of the literature
1 Department of Palliative Medicine, Royal Marsden and Royal Brompton NHS Foundation Trusts, London, UK 2 Department of Palliative Care, Policy and Rehabilitation, King's College London, Cicely ...
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Unilateral post-tuberculous lung destruction: the left bronchus syndrome.
In a prospective study of 13 patients requiring pneumonectomy for unilateral post-tuberculous lung destruction the left side was found to be affected in 12. Review of a further 172 cases showed the ...
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Fluorescence bronchoscopy for the early detection of lung cancer
University College London Hospitals, Department of Thoracic Medicine, The Middlesex Hospital, Mortimer Street, London W1N 8AA, UK Dr P J M George. If you wish to reuse any or all of this article ...
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Induced sputum examination: diagnosis of pulmonary involvement in Fabry's disease
Asthma Research Group, Department of Medicine, St Joseph's Hospital and McMaster University, Hamilton, Ontario, Canada Dr F E Hargreave, Firestone Regional Chest and Allergy Unit, St Joseph's Hospital ...
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BAL findings in a patient with pulmonary alveolar proteinosis successfully treated with GM-CSF
Background: Idiopathic pulmonary alveolar proteinosis (PAP) has recently been recognised as a disease of impaired alveolar macrophage function caused by neutralising anti-granulocyte-macrophage colony ...
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Case-control study of severe life threatening asthma (SLTA) in adults: demographics, health care, and management of the acute attack
BACKGROUND Severe life threatening asthma (SLTA) is important in its own right and as a proxy for asthma death. In order to target hospital based intervention strategies to those most likely to ...