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Anti-Aβ antibodies (Aβ-Abs) that bind specific Aβ variants are essential research tools. Furthermore, the monoclonal Aβ-Abs Aducanumab, Lecanemab, and Donanemab have recently gained approval as the ...
Once the antibody binds, the fibril is locked in this state, and further growth is prevented. This finding reveals a promising new approach to stopping Aβ fibril growth and, potentially, slowing ...
[13] A phase III trial is underway. Another immunologic strategy involves intravenous immunoglobulin (IVIgG) which contains antibodies against Aβ. These antibodies selectively target Aβ and are ...
which is a non-Aβ specific antibody. This project uses techniques such as fluorescence and multi-dimensional NMR. The second project will determine the Met35 oxidation rates of the Aβ(1-40) and ...
This authorisation makes the amyloid-beta (Aβ) monoclonal antibody the first to address the underlying cause of Alzheimer's in the European Union (EU). It extends to all 27 member states ...