Importantly, transplant patients with higher levels of Siglec-7 and Siglec-9 showed better graft survival, highlighting this pathway as a promising target for new therapies. Skip to main content ...

The paper explains how monogenic and polygenic factors converge on key growth pathways and influence disease risk. Skip to content. Menu. Medical Home Life Sciences Home. Become a Member.

Since abiraterone acetate and enzalutamide target the same pathway, response will be evaluated in combination in the signal-seeking phase 2 portion of the study. As of October 2024, 2 patients have ...

Researchers at the NYU Pain Research Center have found a new receptor for nerve growth factor that plays an important role in pain signaling, even though it does not signal on its own, according ...

Obesity is a chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial ...

Label-free biosensor assay detects Toll-like receptor signals and even discriminates between different signaling pathways. genprowebdirectory Facebook Linkedin RSS Twitter Youtube ...

Poster Number: P0284. Additional details on the meeting can be found at the 31 st Annual ESGCT Congress website.. About TSHA-102 TSHA-102 is a self-complementary intrathecally delivered AAV9 ...

BACKGROUND: HCC-1 (hemofiltrate CC chemokine-1), a CC-type chemokine, exerts function to change intracellular calcium concentration, induce leukocyte, and manipulate enzyme release especially in ...

Understanding these two pathways could lead to the development of better therapies for opioid addiction (SN: 3/31/19). “It’s pie in the sky right now, ...

An AAV9 targeting the transferrin receptor delivered the gene for mScarlet fluorescent protein throughout the brain (top), but an AAV9 carrying the same gene could not (bottom). [Courtesy of Huang et ...

In an important step toward more effective gene therapies for brain diseases, researchers from the Broad Institute of MIT and Harvard have engineered a gene-delivery vehicle that uses a human protein ...

The team said that the new AAVs are ideal for gene therapy because they target a human protein and have similar production and purification yields as AAV9 using scalable manufacturing methods.