More than 90% of patients with inflammatory bowel disease (IBD) accepted the switch from the adalimumab reference product to adalimumab biosimilars, with favourable survival and remission outcomes ...

A molecule named NM102 selectively inhibits the Mfd protein, a bacterial virulence and mutation factor, thereby disarming pathogenic bacteria without affecting beneficial microbiota.

As an undergrad at Harvard, Danna Freedman went to a professor’s office hours for her general chemistry class and came across an elegant paper model that depicted the fullerene molecule.

On April 14, 2025, Celltrion, Inc. announced that the U.S. Food and Drug Administration granted an interchangeable designation to YUFLYMA (adalimumab-aaty), its biosimilar referencing HUMIRA ...

Small-molecule drug investment has fallen 68%—and 74% for diseases mainly affecting Medicare patients—since the IRA was introduced “This decline in innovation means fewer options at a higher ...

Takeda has returned to BridGene Biosciences for another small-molecule collaboration—this time focused on immunology as well as neurology. BridGene’s pursuit of undruggable targets is enabled ...

For psoriatic arthritis, four small-molecule drugs were all superior to placebo and comparable with adalimumab. Upadacitinib and deucravacitinib consistently were in the top two across efficacy ...

With the recent surge in popularity of weight loss drugs like Ozempic, altogether called GLP-1s, there has been renewed scientific interest in understanding how our bodies regulate muscle growth.

Prospective small molecule NFAT inhibitors were evaluated at a concentration ... Ninety-six-well microtiter plates (Corning, United States) were coated with 0.88 μg/mL of adalimumab (AbbVie Inc., ...

Adalimumab (brand name Humira ... Advanced combination treatment with biologic agents and novel small molecule drugs for inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2023;19(5):251-263. Gu ...

Overview: Adalimumab is a medicine you inject under the skin. It is used for inflammatory or immune problems, such as certain types of arthritis, gut conditions, skin conditions, and an eye ...