The Max Planck Institute of Biophysics is a leading international research institute that uses biophysical, biochemical and computational methods to investigate the structure, dynamics and function of ...

Abstract: Accurate prediction of the drug binding between proteins and ligands can significantly advance the development of structure-based drug design ... based methods to learn representations of ...

Department of Chemistry, University of New Mexico, Albuquerque, New Mexico S7131-1096, USA Current Address: Department of Chemistry, Kansas State University, Manhattan, Kansas 66506-3701, USA ...

This protein, MCL-1, is a powerful agent in regulating cell death – and if levels are lowered, by way of outside forces such as stress, aging, cancer drugs or genetics, HSFCs are left vulnerable ...

solving a decades-long mystery by determining the first structure of the human protein PINK1 bound to mitochondria. First discovered more than 20 years ago, PINK1 is a protein directly ...

To liberate iron from eukaryotic iron binding proteins, a wide variety of microbes synthesize and secrete low molecular weight ... a periplasmic transport protein, and a complex of inner membrane ...

PySSA can help make protein structure ... molecular biology, and for teaching. In addition to the prediction and analysis capabilities, PySSA has a more user-friendly interface for interacting with ...

Since amino acids regulate mTORC1 activity, the researchers fed pregnant mice either low-protein or high-protein diets starting at E6.5. They found that low-protein diets reduced the overall size of ...

One unique substitution Gly(G)299Glu(E) in the capsid protein VP2 was first identified with ... in the VP2 gene of giant panda-sourced FPV affected the overall structure of the capsid, molecular ...

Proteins by and large carry out their molecular functions in a folded ... amino acids between distant positions within a protein sequence allows for the inference of long range contacts to facilitate ...

Players of an online game that allows users to adjust how proteins are folded have solved a decade-long protein structure mystery ... in Nature Structural and Molecular Biology. “This is the real deal ...