Aminoglycosides are a class of antibiotics used to treat serious infections caused by bacteria that are difficult to treat. Aminoglycosides are called bactericidal antibiotics because they kill ...

Aminoglycosides, a class of antibiotics, were the first drugs found to help ribosomes read past these incorrect stop signals. But they come with a serious catch: high doses are needed to work, and ...

Translation occurs at a reduced rate in bacterial persisters 2,8, indicating that they should be susceptible to aminoglycosides, which are ribosome-targeting bactericidal antibiotics 9,10,11,12,13 ...

Gentamicin treatment caused a significant reduction in basal potential difference in the 19 patients carrying stop mutations (from –45±8 to –34±11 mV, P=0.005) and a significant response to ...

An expert briefly describes the study ‘Single Dose Aminoglycosides versus Carbapenems for the Treatment of Uncomplicated Urinary Tract Infections Caused by Extended-Spectrum β-lactamase ...

NEW ORLEANS, LA—Extended-interval aminoglycoside dosing “appears of be safe in pediatric patients,” a retrospective study presented at IDWeek has found.—Extended-interval aminoglycoside dosing ...

Researchers at the University of Kentucky's College of Medicine have found that a class of antibiotics called aminoglycosides could be a promising treatment for frontotemporal dementia.

Side effects. Aminoglycosides can override the stop signal on their own, but this requires a very high dose, causing many side effects. As mefloquine boosts the efficiency of aminoglycosides, the ...

Background: Empiric dosing of gentamicin has not been evaluated in critically ill neonates with unrepaired congenital heart disease (CHD). Many factors may alter gentamicin pharmacokinetics in ...

Aminoglycoside-induced AKI developed in 65 patients (12%) after a median duration of 11 days; 56%, 29%, ... - Conference Coverage - Full-Length Features - Drug Monographs ...

Aminoglycosides have limited clinical use in humans, but are often a last resort for treating multi-resistant infections. ... The most comprehensive sci-tech news coverage on the web.

A total of 195 patients completed the study. They received 80 to 160 mg of gentamicin twice daily by intravenous infusion (generally for 5 to 7 days) and were randomly assigned to receive 14 days ...