Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

Zilovertamab vedotin, an antibody drug conjugate (ADC) developed by Merck & Co (MSD) to treat diffuse large B-cell lymphoma ...

Merck's ( NYSE: MRK) experimental antibody drug conjugate zilovertamab vedotin, in combination with standard of care, ...

To better compare belimumab’s efficacy with results from phase 3 trials of obinutuzumab, investigators conducted a post hoc analysis of patients with active proliferative lupus nephritis in the MMF ...

The antibody PLT012 targets the fat transporter CD36 to restore immune responses in tumors, offering a new and promising ...

Interestingly, after adding in anti-GFP antibodies, identical dose–response curves were observed for both anti-DNA-positive patient plasma and normal plasma (Figure S6). This observation is consistent ...

Primary studies frequently report test accuracy analysis such as receiver operating characteristic (ROC) curves and test accuracy ... specificity of using anti-TNFs or antibodies produced against anti ...

Importantly, the dose–response curve for passive antibody administration is parameterised from different studies using intramuscular and intravenous administration. However, studies showed a ...

Yu et al. noted a bell-shaped response curve, with an optimal dissociation constant around an intermediate value of 50 nM. A similar binding-affinity range of agonist antibody variants against ...

Finally, the researchers assessed the total antibody response up to 15 days after the booster vaccination, represented as the area under the curve (AUC). The researchers analyzed 199 milk samples ...

The end points of this study were objective response rate (ORR), progression-free survival ... The final model for predicting ORR (area under the curve [AUC] = 0.71) in immunotherapy-treated patients ...

The curve equation is as follows ... Characterization of the Anti-AMG 966 Antibody Response The AMG 966 PK assay utilizes two anti-idiotype antibodies and only measures free AMG 966 that is not bound ...