The AlphaRED docking strategy demonstrates a new and better way to predict protein complex structures within feasible compute times. This work is particularly impactful for its success rate on ...

Nanobodies, tiny, single-domain antibody fragments derived from camels and sharks ... However, challenges persist, particularly in modeling kinked CDR3 loops and in antigen-docking accuracy—where ...

Such reproductions, however, appear to be running into the same issues, indicating that global antibody-antigen docking/co-folding is still out of reach, and to get at reasonable models one needs to ...

Learn how antibody to payload design is crucial for advancing ADC technology in oncology and beyond with expert insights.

Researchers at the Ragon Institute have made a significant discovery about how antibodies can directly enhance the body's ...

Singapore's national platform for drug discovery and development, has announced the presentation of updated clinical data for ...

[Karena Yan, Nabla Bio] “During my PhD work on antibody antigen structure work for malaria vaccine design, the idea of choosing a site on a malaria protein and then designing an antibody on a ...

"Even in Hitler’s Germany, you could cross the Alps to Switzerland. You could hide in an attic like Anne Frank did." ...

3) Biolojic Design: Founded in 2009, the Israeli company uses a structure-based approach, where their model is trained on millions of Antibody-Antigen pairs in order to identify a template ...

In recent years, the therapeutic landscape for hematological malignancies has undergone a profound transformation, driven by the development and regulatory ...