Singapore's national platform for drug discovery and development, has announced the presentation of updated clinical data for ...

Nanobodies, tiny, single-domain antibody fragments derived from camels and sharks ... However, challenges persist, particularly in modeling kinked CDR3 loops and in antigen-docking accuracy—where ...

Accurately predicting antibody–antigen interactions, which are central to the adaptive ... score is modeled by extreme value distributions of the scores from rigid-body docking decoys. For ...

1. Open the Colab notebook (Fold_Dock.ipynb, link above). 2. Input antibody sequence - Select antibody input type (a fasta file or an antibody sequence). Separate the light and heavy chains with ':' ...

Protein-protein docking is being developed to model the structure of ... we developed a new dataset generated by high-quality antibody-antigen complexes. The result in this antibody-antigen dataset ...

We constrained docking to interact with the residues composing the ... In this work, we focused on antibody–antigen interaction, a relevant case of molecular recognition. We applied our recently ...