Tretinoin is endogenously formed in the skin from all- trans retinol by basal keratinocytes. Both all- trans retinoic acid (tretinoin) and all- trans retinol are naturally occurring retinoids. The ...

An autologous cell-based gene therapy, prademagene zamikeracel uses patients' genetically modified keratinocytes, altered to produce functional type VII collagen. Sheets of the therapy are ...

Wrong on skin care: keratinocytes, not fibroblasts, make collagen for healthy skin Keratinocytes produce collagen fibers, while deeper fibroblasts later modify the collagen fibers initially formed ...

We clarified that keratinocytes are primarily responsible for dermal collagen formation,” explains Ayaka Ohashi, a Ph.D. student at the Graduate School of Environmental, Life, Natural Science ...

By using a specialized 3D printer to deposit fibroblasts into specially-designed culture vessels, adding keratinocytes on top of this layer of fibroblasts, and incubating the cells in several ...

Histopathological examination of the skin demonstrated dyskeratotic keratinocytes within the superficial epidermis and cornified layer. Vacuolar interface change and apoptotic keratinocytes were ...

We asked six dermatologists all about dark spots, like what causes them and how to to treat them, plus their favorite dark spot correctors that’ll even skin tone fast.

Hydrogen molecules possess a range of biological effects, including antioxidant, anti-inflammatory, and anti-apoptotic properties. These attributes suggest potential therapeutic benefits in treating ...

The heterogeneity of these keratinocytes subpopulations was mapped into spatial context using state-of-the-art multiplex imaging. Researchers found that tooth-facing sulcular keratinocytes (SKs) and ...

The pathogenesis of photosensitivity involves the accumulation of apoptotic keratinocytes, which release SLE-associated autoantigens upon UV exposure. This study investigates whether heterozygous ...

Journal reference: Kobayashi, R., et al. (2023) The EGF/EGFR axis and its downstream signaling pathways regulate the motility and proliferation of cultured oral keratinocytes.

The stratum corneum is the top layer of your epidermis (skin). It protects your body from the environment and is constructed in a brick-and-mortar fashion to keep out bacterial and toxins.