† Departments of Neurobiology and Biomedical Engineering, University of Alabama, Birmingham, Alabama 35294, United States ‡ Departments of Chemistry and Chemical Engineering and Center for Nanoscale ...

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This study served as an exploratory study investigating astrocyte to neuron reprogramming as a potential treatment for ischemic stroke using a canine model to assess anatomical and functional recovery ...

Astrocytes generally perform protective roles, such as the release of neurotrophic factors, glutamate metabolism, transfer of healthy mitochondria to neurons, and maintenance of the blood-brain ...

The brain also contains billions of astrocytes — star-shaped cells with many long extensions that allow them to interact with millions of neurons. Although they have long been thought to be mainly ...

Get Instant Summarized Text (Gist) Astrocytes, previously considered mainly supportive, may significantly enhance the brain's memory storage by mediating complex interactions among neurons ...

The brain also contains billions of astrocytes - star-shaped cells with many long extensions that allow them to interact with millions of neurons. Although they have long been thought to be mainly ...

We will begin by highlighting a subset of the many cellular functions of astrocytes, focusing specifically on those functions that have the most relevance to neurodegeneration (Figure 1).

This study, carried out on animal models with the disease, describes for the first time the decisive role of the RTP801 protein in cells known as astrocytes during the progression of this ...

Real-time imaging of ATP release from astrocyte cells has been reported. However, the observed chemiluminescence propagation wave reflects both ATP release and diffusion in the extracellular bulk ...

In the early phase of Alzheimer’s disease, astrocytes are the primary source of APOE in the brain. This study examined the effects of astrocyte-derived human APOE isoforms in APOE-deficient mouse ...