In a story of collaboration and community, researchers identified intergenerational epigenetic changes caused by war and trauma in Syrian refugees. When you purchase through links on our site ...

The analysis also underscored the stability of allele-specific DNA methylation regions (ASMRs) and their limited shift during the regeneration process. These findings suggest that epigenetic ...

Their work is described in a new Cell paper titled, “Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration.” According to ...

Testing included tracking gene activation, measuring the microscopic new myelin sheaths surrounding axons, and observing that ... highlights the potential of targeting epigenetic silencing to enable ...

More information: Xu Wang et al, Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis, Neuron (2022). DOI: 10.1016/j.neuron ...

Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis. Neuron , 2022; DOI: 10.1016/j.neuron.2022.10.028 Cite This Page : ...

Activating Regrowth with Epigenetic Therapy. Continuing their past success, the researchers utilized a tiny molecule called TTK21 to activate genetic programming that induces axon regeneration in ...

The mechanisms involve an epigenetic regulation of gene transcription ... (6-10) In this study, in an effort to discover new pharmacological modalities to aid in axon regeneration, we employed ...

Researchers used a small molecule called TTK21 to activate genetic programming that induces axon (nerve fibre) regeneration in neurons. TTK21 changes the epigenetic state of genes by activating the ...