Spinal cord injury (SCI) is a devastating, debilitating, and life-altering condition that currently lacks a definitive cure or highly effective treatment ...

The axolotl is renowned for its extensive ability to regenerate organs and body parts, including its spinal cord. Studies on ...

Homeostasis is the ability of living organisms to maintain stable internal conditions, such as temperature, hydration and ...

Our results support that OECs are a unique hybrid glia, some with progenitor characteristics, and that their gene expression patterns indicate functions related to wound healing, injury repair, and ...

This paper describes a new in vitro model for DRG neurons that recapitulates several key differences between the peripheral and central branches of DRG axons in vivo ... a 3D-like environment, as DRG ...

Unfortunately, axonal regeneration is greatly impaired in aged organisms ... successful axonal growth and functional recovery require that Schwann cells, glial cells which surround and support neurons ...

Glial cells are an integral part of the human nervous ... a fatty material that wraps around a portion of the nerve cell — called the axon — to insulate them and enable faster electrical ...

“We found that glia have a metabolic switch associated with glucose metabolism that when triggered reverses inhibitory effects on growth and promotes axon regeneration,” commented Shuxin ...

“We found that glia have a metabolic switch associated with glucose metabolism that when triggered reverses inhibitory effects on growth and promotes axon regeneration,” explained Shuxin Li, MD, PhD, ...

Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States Growth-associated protein-43 (GAP-43) and brain acid-soluble protein 1 (BASP1) regulate actin ...