many current molecular property prediction models are based on 2D molecular graphs, neglecting the 3D characteristics of molecules. Therefore, in this paper, we propose the structure-based robust ...

A new study led by researchers at the Earth-Life Science Institute (ELSI) at Institute of Science Tokyo has uncovered a surprising role for calcium in shaping life's earliest molecular structures.

The detection of structure-specific interactors of disease-associated protein structural states should provide novel molecular insights into disease mechanisms and suggest new therapeutic targets. LiP ...

Neo-1 is the first model to unify de novo molecular generation and atomic-level structure prediction in a single model, by generating latent representations of whole molecules instead of ...

Yes! I want to get the latest chemistry news from C&EN in my inbox every week. ACS values your privacy. By submitting your information, you are gaining access to C&EN and subscribing to our weekly ...

SAN FRANCISCO, Dec. 17, 2024 (GLOBE NEWSWIRE) -- Structure Therapeutics Inc. (NASDAQ: GPCR), a clinical-stage global biopharmaceutical company developing novel oral small molecule therapeutics for ...

Our group investigates the molecular mechanisms of transcriptional regulation ... The structural information is used to build structure-based hypotheses that will be tested in biochemical and ...

A new study has revealed for the first time the molecular structure of brains affected by Alzheimer's disease. Researchers have produced 3D models of proteins in the brain, including two proteins in ...

Understanding its Lewis structure, molecular geometry, hybridisation, and polarity helps in knowing its behaviour and interactions. Who gave the Lewis Structure? Lewis structures were introduced ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

In a new publication in Cell, scientists from the Departments of Bionanoscience and Imaging Physics now describe the molecular structure of these vesicles for the first time. These gas vesicles ...