These proteins are part of a shuttling mechanism that bacteria use to pump out a wide ... The MacAB-TolC complex, known as a multidrug efflux pump, spans the cell’s inner and outer membranes ...

By modifying these “efflux pumps” to recognize the antibiotic, bacteria can eliminate the drug before it poisons them. As it turns out, some phages appear to use these same efflux pumps to ...

By modifying these “efflux pumps” to recognize the antibiotic, bacteria can eliminate the drug before it poisons them. As it turns out, some phages appear to use these same efflux pumps to ...

For example, structures called "efflux pumps" in the cell membrane allow bacterial cells to pump out antibiotics that get inside the cell. Bacterial cells can also make enzymes that chemically ...

2. Expel the antibiotic if it gets in. Bacteria have machinery known as efflux pumps, which regurgitate unwanted molecules from within the bacteria. Bacteria can alter the pump so it is more ...

Now, scientists have demonstrated a new way to counter one of the most effective bacterial defense strategies. Some species have evolved efflux pumps – proteins on the bacterial membrane that ...

Bacteria that have mutated to become particularly resistant to antibiotics often have many of these efflux pumps on their surface. To counter this defense, researchers have produced a class of ...

Many bacterial cells defend themselves against antibiotics by expelling the drugs using multidrug efflux pumps. Unlike many other transporters, which only work with single compounds, such protein ...

And not only that, Petersen says this kind of efflux pump mechanism is also used by antibiotic-resistant bacteria, so there is potential for these findings to lead to better antibiotic treatments.