Large gaps in basement membrane occur at sites of cell invasion and tissue remodelling in development and cancer. Though never followed directly in vivo, basement membrane dissolution or reduced ...

Basement membrane (BM) proteoglycans are more than charged filtering agents. These complex macromolecules can direct cell responses by a wide range of sophisticated mechanisms. BM proteoglycans ...

Studying basement membranes is challenging, however, because they are best studied in an intact animal. If you remove them from the animal, Page-McCaw said, you change their organization and their ...

Renibus Therapeutics® ("Renibus"), announced that the U.S. Food and Drug Administration (FDA) has granted Orphan Drug ...

Their results, reported in Proceedings of the National Academy of Sciences (PNAS), demonstrated that while this basement membrane is elastic, it also become stiffer as it expands. The team ...

4 Science. The bond — never before seen in living things — was found buried in the basement membrane, a tough, structural layer of cells that surrounds most tissues. A greater understanding of ...

Most tumors are sheathed in a protective "basement" membrane -- a thin, pliable film that holds cancer cells in place as they grow and divide. Before spreading to other parts of the body ...

We describe two patients in whom anti–glomerular basement membrane disease developed after treatment with alemtuzumab.

Drug screening in 3D cell cultures is possible with the right tools. Amid cuts to federal funding, US universities tighten budgets, forcing PhD students and early-career researchers to navigate an ...