Endoplasmic reticulum (ER)-associated protein degradation (ERAD) eliminates misfolded or unassembled proteins from the ER. ERAD targets are selected by a quality control system within the ER lumen ...

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Minor groove-binding ligands are able to control gene expression and are of great interest for therapeutic applications. We extracted hydrogen-bonding geometries from all available structures of minor ...

This collection highlights studies published in our recently launched Methods section. We are very excited to see that our Methods section has quickly expanded and offers a home to a broad variety of ...

An NHS hospital trust drafted guidance proposing extra breaks for transgender staff who wear chest binders or tuck their genitals, but has since dropped the proposals following criticism and the ...