Scientists at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget), Milan, have found that gene editing using ...

Researchers have identified an early postnatal window that allows gene transfer to circulating blood stem cells, advancing ...

Whether you are a competitive athlete or an older adult, strong bones are essential—not only for movement, but also for ...

Innate lymphoid cells (ILCs) are newly identified members of the lymphoid lineage and have emerged as important effectors of innate immunity and tissue remodeling. ILCs are characterized by 3 main ...

New long-term CARTITUDE-1 data show one-third of patients treated with CARVYKTI® remain progression-free CARTITUDE-4 analysis shows compelling overall survival and ...

Kyle Registre's childhood dream of becoming a pilot can finally come true now that he says he's been cured of sickle cell complications.

Cell-lineage trees in recipients and donors suggested ... during the early phase of rapid expansion in the recipient’s bone marrow. The differentiation patterns of these stem-cell clones were ...

Culley thinks of Lineage Cell Therapeutics as a cell transplant company. To take the company down this path, he’s looked at cells already used for allogenic cell transplants. Take bone marrow ...

Together, we showed that osteocytes play critical roles in regulation of lineage cell specifications in bone and bone marrow through mediation of senescence. The work provides a new understanding of ...

Historically, bone marrow adipocytes were regarded as one of the terminal states of skeletal stem cells, which stand at the pinnacle of the lineage and possess trilineage differentiation potential ...

BM, bone marrow; C, cortical bone; white arrow ... To explore the adipogenic characteristics of osteoblast lineage cells in response to rosiglitazone treatment, we examined PPARγ expression.

Bone marrow adipose lineage cells are essential RANKL sources for trabecular osteoclast formation and bone resorption in the context of pathological bone loss. The Adipoq Cre line targets bone marrow ...