The human brain is comprised of two main types of cells, known as neurons and glia. The first are responsible for ...

New research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Jim FessendenUMass Chan Medical SchoolNew research by Sumeda Nandadasa, PhD, reveals how a key protein associated with Meckel-Gruber syndrome ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

Genetic screen for retrograde IFT defects uncovers a temperature‐sensitive (ts) mutation in C. elegans CHE‐3 (dynein‐2 heavy chain). Paraquat‐resistant strains were first screened for dye‐filling ...

The team chose to study glia, dendrites, and cilia in the nematode C. elegans, a model organism cherished by basic researchers for its straightforward genetics and well-studied biology.

The transmembrane protein KCC-3 (green) localizes to a microdomain in the C. elegans Amphid Sheath glia (magenta), around just one of its 12 associated neurons. This localization pattern underlies the ...

Molecules and Cells 36 (4): 288-303. PMID: 24048681 2013 Olivier-Mason A, Wojtyniak M, Bowie RV, Nechipurenko IV, and Sengupta P. Transmembrane protein OSTA-1 shapes sensory cilia morphology via ...

C. elegans is a transparent nematode roundworm that actively moves away from a light stimulation spot. I was fascinated by how the light sensation is regulated in a worm with no eyes.

Results from their study are published in the journal Developmental Cell in a paper titled, “ A cilia-independent function of BBSome mediated by DLK-MAPK signaling in C. elegans photosensation.” ...

A cilia-independent function of BBSome mediated by DLK-MAPK signaling in C. elegans photosensation. Developmental Cell, 2022 DOI: 10.1016/j.devcel.2022.05.005 ...