Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

Researchers found the therapy downregulated VEGF expression and improved retinal thickness in neovascular age-related macular degeneration patients.

In gene and cell therapy, RNP-mediated CRISPR gene editing is quickly emerging as the new norm. For many gene editing firms, GenScript has created hundreds of Cas9, Cas12a, Cas13a, MAD7, ABE, CBE ...

The University of Bayreuth's Biomaterials research group has, for the first time, successfully applied the CRISPR-Cas9 ...

Using advanced proteomics technologies, research teams from the Shanghai Institute of Nutrition and Health at the Chinese ...

The human gut is home to trillions of microbes that not only aid in digestion, but also play a key role in shaping our immune ...

After 3 doses of tailor-made treatment, an infant with a rare, life-threatening urea cycle disorder is thriving ...

[Photo/CAS official website] ScienceOne introduces two innovations — an AI-powered literature assistant that scans thousands of academic papers to draft summaries and identify research trends, and a ...