A new platform comprehensively profiles CAR T-cells during manufacturing, revealing phenotypic shifts. This allows for ...

BACKGROUND: T cells are central to the immune responses contributing to hypertension. LGMN (legumain) is highly expressed in T cells; however, its role in the pathogenesis of hypertension remains ...

CD4 + T cells play a crucial role in orchestrating adaptive immune responses against pathogens, guiding a complex array of signals and differentiation processes. Following their priming in secondary ...

CD4 and CD8 cells are both types of white blood cells called T cell lymphocytes. Some of your T cell lymphocytes direct other cells of your immune system on when and where to attack invaders, kind ...

More information: Panpan Jiang et al, Dedicator of cytokinesis 8 (DOCK8) mutation impairs the differentiation of helper T cells by regulating the glycolytic pathway of CD4+ T cells, MedComm (2024 ...

Study: Temporal profiling of CD4 T-cell activation and differentiation upon SARS-CoV-2 spike protein immunisation.Image Credit: Kateryna Kon/Shutterstock *Important notice: bioRxiv publishes ...

Using thymic stromal lymphopoietin cytokines, researchers targeted the Th cells to the tumor, where they released cytokines, IL-3, IL-5, and GM-CSF. According to Demehri, the team demonstrated that ...

Preliminary scientific report. Heather Long, Emily Tye, Elizabeth Jinks et al. (2022). Broad SARS-CoV-2 spike-specific CD4+ T-cell response preserves recognition of variants of concern.