CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the ...

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

At first glance, some people seem to have recovered from COVID-19. They no longer test positive and can return to work or ...

With immunotherapy increasingly making it out of the lab and into hospitals as a viable way to treat serious conditions like ...

During a live event, Neal E. Ready, MD, and participants discussed what factors justify using PD-1 plus CTLA-4 inhibitor and ...

Michael Green, PhD, discusses a new method of assessing lymphoma subtypes utilizing the tumor microenvironment.

Whether antiretroviral therapy (ART) is always completely suppressive, or HIV might continue to replicate at low levels despite ART in some people with HIV (PWH), is still debated. Here, we ...

There are two ways that HIV patients’ bodies can keep the virus under control after they stop antiretroviral therapy, a new study led by Dr. Anthony Fauci, director of NIAID, and Tae-Wook Chun, chief ...

Nigel McCracken, chief operating officer, Virax Biolabs, discusses new findings that reveal altered cytokine activity and evidence of T cell exhaustion in long COVID patients, providing deeper insight ...

The lever that determines immune cell fate One type of T cell—known as a CD8—is constantly on the prowl in the human body in search of intruders that can cause infections and disease.

Findings reveal that metabolic enzymes ACSS2 and ACLY regulate T cell exhaustion, linking nutrient metabolism to epigenetic changes in immunity.

A study uncovers that CD8+ T cells in ME/CFS patients exhibit exhaustion-like states, a condition linked to chronic immune activation. This discovery raises the possibility of adapting cancer ...