Fatty diets and obesity affect the structure and function of astrocytes, the star-shaped brain cells located in the striatum, ...

A breakthrough in the understanding of how mammals create red blood cells could lead to opportunities for artificial blood to ...

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor ...

Many people with IBD, an umbrella term that includes ulcerative colitis and Crohn's disease, have a reduced quality of life, ...

It elucidated the novel mechanism by which Trp-CA activates MRGPRE, promoting GLP-1 secretion through dual pathways: Gs-cAMP signaling and β-arrestin-1-mediated ALDOA phosphorylation, thereby ...

JINAN, China, June 23, 2025 /PRNewswire/ -- On May 29, 2025, Professor Sun Jinpeng's team and Professor Yu Xiao's team at Shandong University, collaborating with Professor Jiang Changtao from Peking ...

Cell Metabolism, launched in January 2005, is one of the newer titles in the Cell Press family. The journal focuses on physiology, with an emphasis on understanding the molecular basis of how the ...

Combining inhibition of SLC22A5-centric carnitine metabolism with anti-PD-L1 agents might be a promising strategy to reverse immune escape in advanced NSCLC. Keywords: Predictive, Prognostic, ...

A Ludwig Cancer Research study has discovered that the metabolic decline that accompanies aging impairs the efficacy of CAR-T cell therapy, an immunotherapy in which T cells of the immune system ...

Aging reduces CAR-T cell effectiveness by impairing metabolism, study shows Researchers identify a decline in NAD levels as a key driver of T cell dysfunction and offer a potential rejuvenation ...

In this editorial, the authors describe the foundations of an N-of-1 gene-editing study to treat an infant with a urea-cycle disorder.