When people think of DNA, they usually think of genes, the parts that code for proteins and drive inherited traits. But there ...

Among the many marvels of life is the cell’s ability to divide and thus enable organisms to grow and renew themselves.

Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

The lab studies chromosome segregation in mammalian oocytes and early embryos. Specific research targets include oocyte-specific mechanisms for chromosome segregation, the diversity of chromosome ...

Research on centromere structure yields new insights into the mechanisms of chromosome segregation errors Date: May 13, 2024 Source: Hubrecht Institute Summary: Researchers have made a surprising ...

Mistakes in chromosome segregation can lead to cell death and cancer development. The researchers discovered that the centromere consists of two subdomains.

A protein complex called the kinetochore connects the centromere of each chromosome to its respective microtubules and is thus vital to chromosome segregation. The ‘constitutive centromere-associated ...

Genetic abnormalities and aberrant expression of genes involved in chromosome segregation and mitosis in patients with chromosomally unstable malignant soft tissue tumors haboring extensive somatic ...

The exchange of DNA between chromosomes during the early formation of sperm and egg cells normally is limited to assure fertility.