Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that ...

Toxoplasma gondii, a parasite, is silently affects brain signaling - possibly altering neural balance even in people without ...

Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that ...

A new study reveals that transplanting healthy human glial progenitor cells into adult mice with Huntington’s disease can delay motor and cognitive decline and extend lifespan.

During the development of peripheral nerves, neural crest cells generate myelinating and non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of the CNS.

For example, glial cells are known to clear away abnormal build-up of protein, accompanied by an inflammatory response; neuroinflammation is a core pathology of AD.

Glial cells (stained red and green) innervate muscle tissue and help coordinate the movement of food through the gut. Photograph: Marissa Scavuzzo.

Beyond that, combining glial replacement with other therapies, such as lowering mutant huntingtin expression and replacing lost neurons, may yield even greater benefits. “While mouse models don’t ...

Infection with a common parasite can seriously disrupt the brain function of intermediate hosts – potentially including ...

Less well understood is what role inflammation and glial changes play. Now, by analyzing single-nuclei RNA-Seq data from more than 400 postmortem brains, scientists have homed in on specific glial ...